Scientific notation works too, like 1.20e3.

The rules in short

Every nonzero digit counts. Zeros between nonzero digits count. Leading zeros never count, since they only place the decimal point. Trailing zeros count only when the number has a decimal point.

So 0.004050 has four significant figures, 100. has three, and 100 on its own has one. Check your instructor’s convention for whole numbers that end in zeros.